Tuesday, December 24, 2019

Can Stem Cells Be Used For Cure Parkinson s Disease Essay

Introduction: Investigative Question: Can stem cells be used to cure a neurological disease, namely; Parkinson’s Disease? The aim of this research is to determine if stem cells can be used to cure Parkinson’s disease. I too aim to determine if such may be achieved by using stem cells that are obtained in an ethically unchallenging manner, such as by using induced pluripotent stem cells, which are created from one’s own skin, to cure the disease. I chose to conduct research into this topic as currently there is no single cure for Parkinson’s Disease. All that currently exists to help the disease’s estimated 7-10 million sufferers are suppressive medicines that do not cure the patients of the disease but better their symptoms thereof. Stem cell therapy, if proven viable, will be the first treatment of the disease that will truly rid the patients of this disease and immediately improve their lives. There is currently much research being conducted regarding the using of stem cells to cure Parkinson’s and whether or not this may be a viable method to do such. To aid in the answering of my question, I researched the progress that different scientists and laboratories across the world have made regarding such by means of the research/experiments that they have conducted. By putting all this information together and examining it I will be able to determine if stem cells can cure Parkinson’s Disease. Reviews of Literature: Source 1: Parkinson’s disease: How Could StemShow MoreRelatedA Research Study On Stem Cell Research Essay1265 Words   |  6 PagesComposition Stem Cell Research According to the Merriam-Webster dictionary a stem cell is â€Å"a simple cell in the body that is able to develop into any one of various kinds of cells (such as blood cells, skin cells, etc.).† There are two types of stem cells, embryonic and adult. The adult stem cells can can be found in brain, bone marrow, blood, etc. The embryonic stem cells come from a four to five day human embryo during the blastocyst phase (Crosta) . The controversy behind the topic usually stems fromRead MoreStem Research : Stem Cell Research1692 Words   |  7 Pages Stem Cell Research As stem cell research progresses, it is essential that we think about the issues encompassing our future. One of the exceptionally debated topics, stem cell research, is gathering a lot of information. Stem cell research is as of now is legal in many nations. The united states, regularly a pioneer in all things new and energizing is one of the last to investigate this topic. As this sort of examination continues advancing, as citizens, we will in all likely need to vote onRead MoreIs Stem Cell Research Ethical?1252 Words   |  6 Pages Is Stem Cell Research Ethical? The question that has been asked so many times, is stem cell research ethical? To argue ethics over this topic, one must first know what a stem cell is.Stem Cells are â€Å"cells with the ability to divide for indefinite periods in culture and to give rise to specialized cells† (Stem Cell Basics: Introduction). The National Institutes of Health say that stem cells are distinguished for two different reasons. The first is â€Å"they are unspecialized cells capable of renewingRead MoreEssay about Advances in Parkinson’s Disease1345 Words   |  6 Pagesall affected by one disease (Parkinson’s Disease Foundation, Statistics). That disease is Parkinson’s disease. Parkinson’s takes away little things like movement that many of us take for granted. Lives are changed because of Parkinson’s, but there is hope. Through medical breakthroughs discovered in recent years, my grandpa and many others suffering from Parkinson’s disease have a ch ance at a better life. History of Parkinson’s Disease Signs or symptoms of Parkinson’s disease have been recordedRead MoreParkinson s Disease And Its Effects1299 Words   |  6 PagesParkinson’s Disease An estimated eight million people are living worldwide with Parkinson’s Disease. Parkinson’s is a disease where the nerve cells, called neurons die in your brain. These neurons that die produce a brain chemical, dopamine which is a neurotransmitter. As the neurons die or become damaged the lack of dopamine creates the symptoms and disease. The neurons that die are located in your Substantia Nigra in the brain. The nerve cell affects your entire nervous system. The neurons transmitRead MoreStem Cells Research The Regeneration Of Medicine. Stem1526 Words   |  7 PagesStem Cells Research the Regeneration of Medicine Stem cells research is one of the most powerful areas of medicine that is both researched and passionately argued. The web page of National Institute of Health (NIH) describes that stem cells are unspecialized cells that are capable of renewing themselves through cell division and they can also be induced to become tissue or organ-specific cells with special functions. Stem cells have the potential to develop into many different cell types in the bodyRead MoreAdvanced Healthcare Treatment Over The Past 20 Years1628 Words   |  7 Pagesthree most significant include Gene therapy, Stem cell transplant and health screening, commencing with meanings, approaches; uses and case studies of each type of techniques. Gene therapy is an experimental form of treatment, where normal genes are placed into missing or defective ones in order to correct or alter genetic disorders. In other terms, it is the therapeutic delivery of nucleic acid polymers into a patient s cells as a drug to treat disease (Gennady, 2015). After many attempts at modifyingRead MoreA Research Study On Stem Cell Therapy1450 Words   |  6 Pagesothers in need. Stem cell therapy is one of the new therapies that are used to treat a disease or prevent it. Bone marrow transplants are one type of therapy that has been used for the treatment of leukemia for a while now. 1,6Stem cell therapy is used to replace damaged, diseased, or malfunctioning cells anywhere in the body with healthy cells. When a stem cell is introduced to a specific part of the body, that stem cell receives signals that tell it how to mimic the other cells around it. OneRead MoreStem Cell Advocacy Paper : Stem Cells1123 Words   |  5 Pages Stem Cell Advocacy Paper Introduction Stem cells are basically the building blocks of life. Some type of these cells can be engineered into any type of cell in the human body. There are three types of stem cells currently. Adult or somatic stem â€Å"cells can generate replacements for bone and muscle cells that are lost through injury, disease or normal wear and tear.† Another type of stem cells are embryonic stem cells. Embryonic stem cells â€Å"are â€Å"starter cells† that can be coaxed into becoming anyRead MoreThe Debate Of Embryonic Stem Cell Research1969 Words   |  8 PagesEmbryonic stem cell research and use is a scientific advancement that could change medical history. There are two types of stem cell research, adult stem cells, and embryonic stem cells. Embryonic stem cells receive a very negative connotation in society, and there are many misconceptions about the process and the ethics of embryonic stem cell research. A large majority of society immediately assume that it is the use of abor ted embryos because of the word embryonic, and adult stem cells are not as

Monday, December 16, 2019

International Business Study Guide Free Essays

string(107) " price in foreign markets due to the application of duties, dealer margins and/or other transaction costs\." IBM 414 Study Guide Ch:12 Global Marketing Management: Planning and Organization Global Marketing – †¢The trend back toward localization –Caused by the new efficiencies of customization –Made possible by the Internet –Increasingly flexible manufacturing processes From the marketing perspective customization is always best †¢Global markets continue to homogenize and diversify simultaneously –Best companies will avoid trap of focusing on country as the primary segmentation variable International Marketing- is the performance of business activities designed to plan, price, promote, and direct the flow of a company’s goods and services to consumers or users in more than one nation for a profit. †¢An entry strategy into international market should reflect on analysis –Market characteristics †¢Potential sales †¢Strategic importance Strengths of local resources †¢Cultural differences †¢Country restrictions à ¢â‚¬â€œCompany capabilities and characteristics †¢Degree of near-market knowledge †¢Marketing involvement †¢Management commitment Exporting Indirect Exporting-requires no equity investment and thus has a low risk, low rate of return, and little control. Licensing –A means of establishing a foothold in foreign markets without large capital outlays –A favorite strategy for small and medium-sized companies –Legitimate means of capitalizing on intellectual property in a foreign market Joint Venures-When two or more participating companies join forces to create a separate legal entity to facilitate doing business in the international arena Direct Investment †¢Factors that influence the structure and performance of direct investments –Timing –The growing complexity and contingencies of contracts –Transaction cost structures –Technology transfer –Degree of product differentiation –The previous experiences and cultural diversity of acquired firms –Advertising and reputation barriers Example:When a company sells to a customer in another country, the company is into Direct exporting. We will write a custom essay sample on International Business Study Guide or any similar topic only for you Order Now Strategic International Allicance Consortia –Similar to joint ventures and could be classified as such except for two unique characteristics †¢Typically involve a large number of participants †¢Frequently operate in a country or market in which none of the participants is currently active –Consortia are developed to pool financial and managerial resources and to lessen risks Joint Ventures –JVs are established, separate, legal entities –The acknowledged intent by the partners to share in the management of the JV There are partnerships between legally incorporated entities such as companies, chartered organizations, or governments, and not between individuals –Equity positions are held by each of the partners Franchise –Franchiser provides a standard package of products, systems, and management services –Franchise provides market knowledge, capital, and personal involvement in management –Expected to be the fastest-grow ing market-entry strategy †¢Two types of franchise agreements –Master franchise †¢Gives the franchisee the rights to a specific area with the authority to sell or establish subfranchises –Licensing Contract Manufacturing-is a manufacturer that contracts with a firm for components or products. It is a form of outsourcing. Contracting Management- is the management of contracts made with customers, vendors, partners, or employees. Contract management includes negotiating the terms and conditions in contracts and ensuring compliance with the terms and conditions, as well as documenting and agreeing on any changes or amendments that may arise during its implementation or execution. CH:8 Developing a global vision though marketing research Challeneges and problems The major difficulty is converting a series of often ambiguous business problems into tightly drawn and achievable research objectives †¢The first, most crucial step in research is more critical in foreign markets because an unfamiliar environment tends to could problems definition †¢Other difficulties in foreign research stem from failures to establish problem limits broad enough to include all relevant variables Environmental Scanning- Careful monitoring of an organization’s internal and external environments for detecting early signs of opportunities and threats that may influence its current and future plans. Marketing Screening- The process of discovering relevant information about a tradable asset in order to determine a fair price for the asset. Primarily used to avoid creating an adverse transaction. Steps to marketing Screening- Market- A regular gathering of people for the purchase and sale of provisions, livestock, and other commodities. Requirements of effective Market Segmentation Describe the psychographic segments profiled in the Worldwide Global Scan study How can international market demand be estimated? page 236 When desired stats aren’t available a close approximation can be made using local production figures plus imports, with adjustments for exports and current inventory levels CH:13 Products and services for consumers Why are product strategy decisions the most crucial ones in the marketing mix? What two errors do multinational product managers tend to commit? Define and explain: Product, Quality Features and benefits Reliability, Durability Product Homologation. What are the standardization/adaptation strategies that a marketer can implement and when would you recommend them? What is meant by the â€Å"diffusion of motivations†? What are the degrees of newness that a product can exhibit and what are the (perceived) product characteristics of an innovation that affect its rate of acceptance? What is product counterfeiting and how can it be fought? CH:14 Products and Services for Businesses ISO 9000 †¢Positively affects the performance and stock prices of firms †¢Certification of the existence of a quality control system a company has in place to ensure it can meet published quality standards –Describes three quality system models –Defines quality concepts –Gives guidelines for using international standards in quality systems Generally voluntary †¢EU Product Liability Directive †¢Now a competitive marketing tool in Europe and around the world †¢The ACSI approach Trade Shows †¢Secondary methods for marketing: –Advertising in print media –Catalogs –Web sites –Direct mail †¢Trade shows have become the primary and most important ve hicle for doing business in many foreign countries †¢Total annual media budget spent on trade events: –Europeans – 22 percent –Americans – 5 percent †¢Benefits –Provide the facilities for a manufacturer to exhibit and demonstrate products to potential users –Allow manufacturers to view competitors products Are an opportunity to create sales and establish relationships with agents, distributors, franchisees, and suppliers †¢Online trade shows –Become useful in difficult economic and/or political circumstances –Are obviously a less than adequate substitute for live trade shows CH:18 Pricing for International Markets Price Escalation- A disparity in pricing where goods have higher costs in a foreign market than in the domestic market due to transportation and exporting costs. Price escalation can also refer to the sum of cost factors in the distribution channels which add up to a higher final cost for a product in a foreign market. The difference between the domestic price and the target price in foreign markets due to the application of duties, dealer margins and/or other transaction costs. You read "International Business Study Guide" in category "Papers" How can the effect of price escalation be lessened? †¢Lowering cost of goods –Manufacturing in a third country –Eliminating costly functional features –Lowering overall product quality †¢Lowering tariffs –Reclassifying products into a different, and lower customs classification –Modify product to qualify for a lower tariff rate within classification –Requiring assembly or further processing –Repackaging †¢Lowering distribution costs Shorter channels –Reducing or eliminating middlemen †¢Using foreign trade zones to lessen price escalation –Establish free trade zones (FTZs) or free ports †¢Tax-free enclave not considered part of country †¢Postpones payment of duties an d tariffs †¢Dumping – To place (goods or stock, for example) on the market in large quantities and at a low price. –Use of marginal (variable) cost pricing –Selling goods in foreign country below the price of the same goods in the home market Gray Market- A market where a product is bought and sold outside of the manufacturer’s authorized trading channels. The unofficial trading of a company’s shares , usually before they are issued in an initial public offering (IPO). †¢Occur whenever price differences are greater than cost of transportation between two markets †¢Major problem for pharmaceutical companies †¢Exclusive distribution Transfer Pricing †¢Prices of goods transferred from a company’s operations or sales units in one country to its units elsewhere –May be adjusted to enhance the ultimate profit of company †¢Benefits –Lowering duty costs –Reducing income taxes in high-tax countries –Facilitating dividend repatriation when dividend repatriation is curtailed by government policy †¢Objectives Maximizing profits for corporation –Facilitating parent-company control –Providing all levels of management control over profitability †¢Arrangements for pricing goods for intracompany transfer –Sales at the local manufacturing cost plus a standa rd markup –Sales at the cost of the most efficient producer in the company plus a standard markup –Sales at negotiated prices –Arm’s-length sales using the same prices as quoted to independent customers Countertrade †¢Types of countertrade –Barter –Compensation deals –Counterpurchase or offset trade –Product buyback agreement †¢Problems of countertrading Determining the value of and potential demand for the goods offered –Barter houses – †¢The Internet and countertrading –Electronic trade dollars –Universal Currency/IRTA †¢Proactive countertrade strategy –Included as part of an overall market strategy –Effective for exchange-poor countries Administered Pricing- The price of a good or service as dictated by a governmental or other governing agency. Administered prices are not determined by regular market forces of supply and demand. Ch:16 Intergrated Marketing Communi cations and International Advertising 6) What are the four methods of promotion and how can they be used in nternational marketing? Integrated marketing communications (IMC) are composed of advertising, sales promotions, trade shows, personal selling, direct selling, and public relations Sales promotions-marketing activities that stimulate consumer purchases and improve retailer or middlemen effectiveness and cooperation Public relations (PR)-creating good relationships with the popular press and other media to help companies communicate messages to their publics-customers, the general public, and governmental regulators. Public relations firms’ billings in the international arena have been growing at double digit rates for some years. Handling such international PR problems as global workplace standards and product safety recalls has become big business for companies serving large companies. International advertising-global mass media advertising is a powerful tool for cultural change, and as such, it receives continuing scrutiny by a wide variety of institutions. What are the pros and cons of standardization, adaptation and â€Å"glocalization† in international advertising? Standardization Pros Standardized marketing for global companies typically offers significant cost benefits. If the same message works universally, you don’t have to spend money to develop customized marketing messages. While you would have to adapt the language to the local markets, the conceptual premise of your messages can remain constant. Also, if your brand theme is powerful and has global appeal, a standardized approach helps people around the world share in the value proposition you offer Cons Global marketing standardization is not sensible in all cases. If people use your products differently or if your brand message doesn’t work everywhere, you need to be flexible. McDonald’s, for instance, has been successful selling its western and American cultural appeal in some countries such as Russia, Japan and France. However, the fast food chain has emphasized its relationship with local suppliers and management in some countries in the Middle East and elsewhere, where attitudes toward western and American culture are less welcoming. Globalization Pros The main benefit of globalization is that it lets you reach a lot more customers. As long as there is demand in an overseas market for a product or service your business offers, there is a customer base. A product that sells successfully at home will often do well in international markets, says Wesley Johnston, a marketing professor at Georgia State University. Electronics and other tech products are examples of consumer goods that sell well on the global market. Cons Before taking your business worldwide, make sure there is a market for it. Consumers in other countries often have different preferences and needs and might not have much interest in buying your product. For example, if you sell Canadian flags, you might not find much demand in countries outside Canada. Another risk of going global is that it can be costly. This is especially true if you decide to set up operations in other countries. Finally, different countries have different regulatory standards. Products that can be made and sold freely in some markets might run up against stiff regulatory hurdles in other countries. Adaptation Explain the statement, â€Å"The search for a global advertising campaign can be the spearhead of the search for a coherent global marketing strategy. What types of errors are committed when advertisers attempt to go global? †¢Consumer criticism †¢Deceptive advertising †¢Decency and blatant use of sex †¢Self-regulation †¢Government regulations What challenges confront international advertisers when they attempt to develop creative and media strategies? †¢Language is one of the major barriers to effective communication through advertising †¢Translation challenges †¢Low literacy in many countries †¢Multiple languages within a country †¢In-country testing with the target consumer group avoids problems caused by linguistic differences ) Can personal selling and sales promotion be standardized in international markets? What role do publicity and public relations play in international marketing? what are the three sources of personnel for international assignments and how can U. S. personnel be trained for such assignments? Expatriates- –Numbers are declining –Important for highly technical or involved products –High cost –Cultural and legal barriers –Limited number of high-caliber personnel willing to live abroad Virtual Expatriates- –Manage operations in other countries but don’t live there Local Nationals Transcend both cultural and legal barriers –Familiar with distribution systems and referral networks –Headquarters person nel may ignore their advice –Lack of availability –Sales positions viewed negatively What are the differences in cultural values that can affect management practices in foreign cultures? How has the profile of global managers changed in recent years? †¢Objectivity –â€Å"Separating people from the problem† †¢Competitiveness and equality –Japanese appear to be the best negotiators with the highest profits –Japanese appear to be more equitable with buyers Time –The passage of time is viewed differently across cultures Describe the negotiation process. Stages 1. Non Task Sounding – Report 2. Task related exchange of info – Sales Pitch †¢Let the foreign counterparts bring up business †¢Expect a large number of questions but little feedback †¢Allow periods of silence †¢Use multiple communication channels †¢Understand the lack of, or the bluntness of negative feedback †¢Meet aggressive f irst offers with questions, not anger 3. Persuasion – Handling of objectives Task-related information exchange versus persuasion †¢Avoid threats, warnings, and other aggressive negotiation tactics †¢Avoid emotional outbursts †¢Ask more questions †¢Use third parties and information channels of communication 4. Consensus agreement – The close †¢Write down concession-making strategies †¢Understand differences in decision-making styles †¢In many cultures, no concessions are made until the end of the negotiations CH 15 International Marketing Channels #8 Describe the difference between traditional, import-oriented distribution systems and modern ones. Page 421 In an imported-oriented or traditional distributution an importer controls a fixed supply of goods, and the marketing system develops around the philosophy of selling a limited supply of goods at high prices to a small number of affluent customers. Describe the current Japanese System; how can an international marketer secure a foothold in the Japanese System? Small retailers are considered to be the foundation of the Japanese distribution system. Distribution in Japan has long been considered the most effective nontariff barrier to the Japanese market. What are the pros and cons of using foreign vs. home country middlemen? Foreign Middlemen-Pros-shorter channels and deal with middlemen in constant contact with the market (page 434) Home Country Middlemen-(domestic middlemen) companies relegate foreign market distribution to others. Offer many advantages for companies with small international sales volume, those inexperienced with foreign markets, those not wanting to become immediately involved with the complexities of international marketing, and those wanting to sell abroad with minimal financial and management commitment. Con- limited control over the entire process. Page 431 What are the strategic goal–the 6C’s of channel strategy? page 436 COST CAPITAL REQUIREMENTS CONTROL COVERAGE CHARACTER CONTINUITY How should you go about locating, selecting and motivating middlemen? page 438 Locating-productivity or volume, financial strength, managerial stability, and capability, and the nature and reputation of the business. Selecting-low volume or low potential volume hampers most prospects, many are underfinanced and some simply cannot be trusted. Motivating- motivational techniques that can be employed to maintain middlemen interest and support for the product may be grouped into five categories: financial rewards, psychological rewards, communications, company support, and corporate rapport. What is the significance of the internet for international distribution and what issues must a prospective e-vendor consider? page 441 Internet is an important distribution method for multinational companies and a source of products for businesses and consumers. Put the consumer in control of marketing and distribution globally #9 What is the purpose of export restrictions? are limitations on the quantity of goods exported to a specific country or countries by a government. Describe the process necessary to determine whether or not an export license is required? An export license is not required Define and explain the following: boycott, free-trade zone (FTZ), maquiladoras, bill of lading, and foreign-freight forwarder. Boycott-is an act of voluntarily abstaining from using, buying, or dealing with a person, organization, or country as an expression of protest, usually for social or political reasons. Sometimes, it can be a form of consumer activism. Free-trade zone-customs privileged (In a FTZ, payment of import duties is postponed until the product leaves the FTZ area and enters the country. Page 536 Maquiladora-is the Mexican name for manufacturing operations in a free trade zone (FTZ), where factories import material and equipment on a duty-free and tariff-free basis for assembly, processing, or manufacturing and then export the assembled, processed and/or manufactured products, sometimes back to the raw materials’ country of origin. Example given in class (Tijuana) Bill of lading-is a document used in the transport of goods by sea. It serves several purposes in international trade. Foreign-freight forwarder-is a person or company that organizes shipments for individuals or corporations to get goods from the manufacturer or producer to a market, customer or final point of distribution. Forwarders contract with a carrier to move the goods. A forwarder does not move the goods but acts as an expert in supply chain management What is physical distribution (logistics)? Involves more than the physical movement of goods. It includes the location of plants and warehousing, transportation mode, inventory qualities and packing. What is the physical distribution concept? Takes into account the interdependence of the costs of each activity; a decision involving one activity affects the cost and efficiency of one or all others. Page 449 What are the pros and cons of the different modes of transport available to international marketers? How to cite International Business Study Guide, Papers

Sunday, December 8, 2019

Health And Well Being Of The Population †MyAssignmenthelp.com

Question: Discuss about the Health And Well Being Of The Population. Answer: After analyzing the discussion, I strongly believe that although, government interventions are designed to promote health and well-being of the population, invariably, it intrudes on personal interests and rights incurring economic costs. Similarly, policy makers also try to inculcate healthier lifestyle choices in individuals where they interfere with economic, political interests and rights of the people. I believe that governments interventions in public health regulations are developed to minimize the risk to others of developing unhealthy lifestyle behaviors, in protecting incompetent people and most importantly, minimize risk to self (Felse, Castelo and Reiner 2013). There are number of levers that are at disposal by government to prevent disease and promote health of the population. Firstly, through education, deterrence or incentives, people are persuaded to make healthy choices, spending powers or taxing greatly encourage healthy behaviors or discourage risk behaviors. Public health regulations also affect the principles of privacy, autonomy and ethnic rights. Despite of the fact that governments power authority is to promote welfare of the society, there are some constitutional limits to public health regulations. This happens because standards of health and safety are different that demand compliance or non-compliance creating individual conflicts (Friedman 2013). Despite of these individual conflicts, research evaluations are important to make better regulations by policy makers. In order to make or shape, health policies are working at a level to transform their health conditions and promote public health safety. Therefore, not only the government who implement public regulation promotes health, but necessarily limits to protection of individual rights. References Felsen, G., Castelo, N. and Reiner, P.B., 2013. Decisional enhancement and autonomy: public attitudes towards overt and covert nudges.Judgment and Decision Making,8(3), p.202. Friedman, D.A., 2013. Public health regulation and the limits of paternalism.Conn. L. Rev.,46, p.1687.